Meaning: A part of the inside of a building that is divided from other areas by walls and a door and that has its own floor and ceiling.
If you mean "room" as in "there is more room in the back of the car." Use other words or phrases, something like HAVE EMPTY SPACE/AREA XI-there.
First 100 words.
As you feel more comfortable with the first few hundreds of ASL signs, progress further with your vocabulary and learn signing more.