Note that this sign has multiple functions and meanings. One is pronoun (e.g. she, he, it) and the other is determiner (e.g. the, this/that). With practice with fluency, a learner may be able to recognize the functions.
Meaning: she (pronoun).
This also can mean HE, IT as well as THE (determiner).
As it has a multiple functions and meanings, you can see that the ASL pronouns SHE and HE are not gender specific.
Grammar-wise, the pronoun has to be spatially inflected properly, depending on the structure of a sentence.
First 100 words.
As you feel more comfortable with the first few hundreds of ASL signs, progress further with your vocabulary and learn signing more.